منابع مشابه
Molecular and genetic analysis of condensin function in vertebrate cells.
We engineered mutants into residues of SMC2 to dissect the role of ATPase function in the condensin complex. These residues are predicted to be involved in ATP binding or hydrolysis and in the Q-loop, which is thought to act as a mediator of conformational changes induced by substrate binding. All the engineered ATPase mutations resulted in lethality when introduced into SMC2 null cells. We fou...
متن کاملStructure and Regulation of Cardiac Molecular Motor Activity
ment, under-appreciated aspects of the role of sarcomeric myosin motors (cross bridges) in regulation of the heart beat. Relatively recent and compelling evidence has substantially expanded the limited textbook view of the role of cross bridges in the heart beat and in regulation of contractility. One aspect of this textbook view is that cross bridges react with actin and undergo state transiti...
متن کاملMolecular adaptations of lipolysis to physical activity
The purpose of the present study was to investigate the context of lipid metabolism research in physical activity, lipolysis, lipolysis hormone regulation and the fate of lipolysis products in exercise, fatty acid transporters, some genes involved in lipid metabolism, effect of resistance activity on lipolysis, adaptations of adipose tissue due to physical activity, lipoproteins and apoproteins...
متن کاملCPF-Associated Phosphatase Activity Opposes Condensin-Mediated Chromosome Condensation
Functional links connecting gene transcription and condensin-mediated chromosome condensation have been established in species ranging from prokaryotes to vertebrates. However, the exact nature of these links remains misunderstood. Here we show in fission yeast that the 3' end RNA processing factor Swd2.2, a component of the Cleavage and Polyadenylation Factor (CPF), is a negative regulator of ...
متن کاملcomparison of catalytic activity of heteropoly compounds in the synthesis of bis(indolyl)alkanes.
heteropoly acids (hpa) and their salts have advantages as catalysts which make them both economically and environmentally attractive, strong br?nsted acidity, exhibiting fast reversible multi-electron redox transformations under rather mild conditions, very high solubility in polar solvents, fairly high thermal stability in the solid states, and efficient oxidizing ability, so that they are imp...
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ژورنال
عنوان ژورنال: Seibutsu Butsuri
سال: 2018
ISSN: 0582-4052,1347-4219
DOI: 10.2142/biophys.58.089